This commentary reflects the author's impressions of Continuing Medical Education (CME) Congress 2012, a provocative international conference on professional development and quality improvement in the health professions that took place in Toronto, Ontario, last spring. The sessions he attended and conversations he had with other attendees were interpreted through the lens of his many years as a scholar and practitioner in adult education as well as his experience and beliefs regarding what the scope of professional development for the health occupations should be. He believes that promoting health and well-being requires that stakeholders understand and act at multiple levels, including the societal (policies, standards, resources), organizational (health care, teamwork, educational), and interpersonal (practitioners, patients, caregivers). The comments he offers in this commentary are intended for anyone in any stakeholder role interested in promoting health and wellness and are organized around three themes: connections, leadership, and inquiry. His reflections include ways to strengthen current professional development.