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ERIC Number: EJ827646
Record Type: Journal
Publication Date: 2009-Mar
Pages: 5
Abstractor: As Provided
ISSN: ISSN-0278-2626
Visual Pathway Deficit in Female Fragile X Premutation Carriers: A Potential Endophenotype
Keri, Szabolcs; Benedek, Gyorgy
Brain and Cognition, v69 n2 p291-295 Mar 2009
Previous studies indicated impaired magnocellular (M) and relatively spared parvocellular (P) visual pathway functioning in patients with fragile X syndrome. In this study, we assessed M and P pathways in 22 female fragile X premutation carriers with normal intelligence and in 20 healthy non-carrier controls. Testing procedure included visual contrast sensitivity and vernier threshold measurements. Results revealed that carriers were selectively impaired on tests of M pathways (low spatial/high temporal frequency contrast sensitivity and frequency-doubling vernier), whereas they showed intact performance on P pathway tests. These results suggest that the deficit of the M pathway is an endophenotype of fragile X syndrome. (Contains 3 figures.)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A