This study seeks to understand how faith community involvement, specifically faith community harmony (sense of belonging and lack of conflict within one's faith community), and faith community interaction (participation in one's faith community) relates to life purpose, loneliness, and well-being among college students. Participants (n = 1253) were undergraduate college students (M = 20; 65% female) attending a private, liberal arts university in Southern California. Participants responded to an online survey on two occasions, one year apart. Measures included the Faith Community Involvement Scale, the UCLA Loneliness Scale, the Perceived Wellness Scale, and the General Life Purpose Scale. Hierarchical regressions found that faith community harmony predicted well-being beyond life purpose and loneliness. Furthermore, faith community harmony and faith community interaction partially mediated the relationship between life purpose and well-being as well as life purpose and loneliness. Discussion focuses on the implications of these findings for a college setting.