This study assessed perceptions about teammate and coach approval of alcohol and other drug use (i.e., injunctive norms) among a sample of 3,155 college student-athletes in their first year of athletic eligibility. Student-athletes perceived that their teammates were more approving of alcohol and other drug use as compared to coaches. A multi-level model analysis indicated that perceived approval from both teammates and coaches were independently associated with student-athletes' alcohol and other drug use behaviors. Future research should explore whether substance use prevention programs that target normative beliefs specific to teammates and coaches may reduce alcohol and other drug use among college student-athletes.