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ERIC Number: EJ991483
Record Type: Journal
Publication Date: 2012
Pages: 2
Abstractor: As Provided
ISSN: ISSN-1470-8175
Proteopedia: 3D Visualization and Annotation of Transcription Factor-DNA Readout Modes
Dantas Machado, Ana Carolina; Saleebyan, Skyler B.; Holmes, Bailey T.; Karelina, Maria; Tam, Julia; Kim, Sharon Y.; Kim, Keziah H.; Dror, Iris; Hodis, Eran; Martz, Eric; Compeau, Patricia A.; Rohs, Remo
Biochemistry and Molecular Biology Education, v40 n6 p400-401 Nov-Dec 2012
3D visualization assists in identifying diverse mechanisms of protein-DNA recognition that can be observed for transcription factors and other DNA binding proteins. We used Proteopedia to illustrate transcription factor-DNA readout modes with a focus on DNA shape, which can be a function of either nucleotide sequence (Hox proteins) or base pairing geometry (p53). (Contains 1 figure.)
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Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A