This study compared the effectiveness of the use of computer-based training (CBT) and instructor-based training (IBT) to train teaching assistants how to use the word processing program Microsoft Word. Thirteen faculty, staff, and graduate student volunteers served as subjects and were randomly assigned to either the computer-based or instructor-based section. Following 10 hours of instruction, students completed a course evaluation and three exercises consisting of an overview of concepts to be covered and a series of commands to be performed on a document. Participants also completed a background survey and a course evaluation questionnaire. Instructor observations on the relative ease for each group of accomplishing various tasks were also used in the assessment. Results demonstrated that the IBT group mastered overall Microsoft Word skills to a greater depth than the CBT group, and suggestions for improving the effectiveness of the computer-based tutorial are offered. Appendixes include the promotional flyer for the class, an outline of course content, sample exercises used for evaluation, and copies of the participant background survey and the questionnaire. (MES)