The intent of this report is to contribute to discussions about what is involved in efforts to implement the type of broad-based, multifaceted system changes seen as essential for fundamentally improving schools. The report begins by stressing four interrelated considerations involved in making multifaceted and complex sustainable changes at a site and systemwide. Then, it highlights how multifaceted interventions exponentially increase implementation complexity. This leads to a discussion of the need to rework operational infrastructure at a site to maximize initial implementation, daily operation, and improvement of multifaceted interventions. The report then moves on to illustrate matters related to pursuing systemwide replication, sustainability, and renewal. It concludes with a look at the necessity of ensuring policy support, and the possible need for policy revision.