Organic chemistry is a required course sequence for many STEM students. However, research indicates that organic chemistry reaction mechanisms are especially challenging for students due to a mixture of underlying conceptual difficulties, the process-oriented thinking inherent to the discipline, and the representations commonly used to depict…

Background: The extent to which students view their intelligence as improvable (i.e., their "mindset") influences students' thoughts, behaviors, and ultimately their academic success. Thus, understanding the development of students' mindsets is of great interest to education scholars working to understand and promote student success.…

In this study, we investigated how students organized their knowledge about organic chemistry reactions in a transformed curriculum, including their choices, abilities, and changes over time. This transformed curriculum focuses on interpreting the underlying mechanistic patterns of chemical reactions and emphasizes the principles of reactivity in…

In the past decade, C-H functionalization has been a very active topic of research in both academia and industry. When a H atom is replaced by an aryl (or heteroaryl) group, the transformation is termed "direct arylation". This approach to the formation of key (hetero)aryl-(hetero)aryl bonds is complementary to traditional methods, such…

This three-year study builds on prior work analyzing students' causal mechanistic explanations about acid-base reactions. Here we extend that work to characterize and investigate how students construct causal mechanistic explanations of simple nucleophilic substitution reactions. After an initial pilot study, we adopted a modified version of the…

To empower high school and undergraduate students to become citizen scientists, we describe the design, construction, and operation of a multisensor device based on Arduino microcontroller technology to record atmospheric measurements relevant to secondary organic aerosols (SOAs). The handheld "AIRduino" multisensor device was built and…

NMR spectroscopy is traditionally taught to students during Organic Chemistry as a tool used for the determination of structures after synthesis. However, modern NMR spectroscopy has many important applications beyond structure elucidation, including molecular profiling of complex mixtures as biofluids and food samples. In this experiment,…

Resonance is a fundamental concept that is necessary for students' successful learning in organic chemistry. However, there is a need to know more about both (1) what students find important when describing resonance and (2) students' conceptual understanding. This research seeks to address this discrepancy by examining second-semester organic…

Herein, we describe an accessible and safe organic chemistry lab experiment that can be completed at home. Liquid-liquid extraction is a fundamental organic chemistry lab experiment that touches on topics such as chemical structure, density, solubility, and acid-base chemistry. Given the increased demand for safe organic chemistry experiments that…

Many recent studies document the difficulties that students experience when learning organic chemistry, often due to the complex visualization and reasoning skills required to successfully understand the ways molecules interact in specific environments. Many of these studies call on instructors to improve their teaching strategies to support…

Curriculum-based undergraduate research experiences (CUREs) have been shown to increase student retention in STEM fields and are starting to become more widely adopted in chemistry curricula. Here we describe a 10-week CURE that is suitable for a second-semester organic chemistry laboratory course. Students synthesize small molecules and use…

This paper describes the design and implementation of a course-based undergraduate research experience (CURE) sequence in chemistry that links a lower-division, organic chemistry course to an upper-division, analytical chemistry course. The focus of student research is on blood preservation using trehalose derivatives in order to mimic the…

Peer learning has become a central feature in many postsecondary classrooms. Many peer learning activities feature near-peer instructors who had previously completed the course and who later serve as peer leaders. There are relatively few examples of activities in which students in a course act as true peer instructors for their classmates. One…

The laboratory experiment regarding esterification of ethylene glycol with acetic acid to ethylene glycol diacetate using resin catalysts in a continuous flow was designed to carry out the reaction in a flow through an inquiry-guided approach. Incorporating the burgeoning field of continuous flow chemistry into the educational infrastructure, the…

As green chemistry and engineering are being integrated into chemical processes in academia and industry, it becomes equally important to equip students with the relevant tools in the fields of sustainable chemistry and processes. In this context, continuous flow technology has been identified as one of the promising strategies. Herein, we…