Resonance is a fundamental chemistry concept first introduced to students in General Chemistry I (GCI), reintroduced in Organic Chemistry I (OCI), and then utilized throughout other higher-level chemistry courses. Student difficulties with resonance are well documented. Instruction is one potential source of student difficulties. What instructors…

Learning gains associated with multiple-choice testing formats that provide immediate feedback (e.g., IFAT®) are often greater than those for typical single-choice delayed feedback formats (e.g. Scantron®). Immediate feedback formats also typically permit part marks unlike delayed feedback formats. The present study contrasted IFAT® with a new…

A course centered around transition-metal catalysis in modern drug discovery was designed to illustrate the central role of organic chemistry in driving small-molecule drug development. The course highlighted both fundamental and applied concepts, first with a focus on the drug discovery process, followed by foundational principles in catalysis…

Research has shown that the use of practical examples in undergraduate education promotes the retention of historically underrepresented students in STEM majors and lowers achievement gaps within courses. Since many students of color and women aspire toward careers in healthcare and the pharmaceutical industry, efforts to incorporate medicinal…

The objective of this study is to determine current medical students' perspective on the importance of Organic Chemistry in premedical curriculum, or if they see more benefit in a taking a different course. Previous literature has focused on premedical students, but the current study focuses on current medical students. A qualtrics survey was sent…

A virtual Game-Based Tournament of Chemistry was developed as an alternative to the traditional problem-solving classes to aid students in reviewing and understanding organic acidity and basicity concepts. The tournament was based on a multilingual virtual board game (English, Portuguese, French, and Italian) which aimed to facilitate students'…

Organic chemistry has been stigmatized as an unduly challenging subject throughout history. However, some undergraduate students excel in the subject when they attempt to understand the content rather than routine memorization. It is evident that rote memorization, a primary result of a student failing to understand the relevance of the material,…

A multistep synthesis of quinolone antibiotic analogues was developed as a laboratory experiment for intermediate/advanced undergraduate students. Students can synthesize a range of "des"fluoroenoxacin analogues via a five-step sequence. The experiment includes a range of key practical laboratory techniques including thin-layer…

Introductory organic chemistry laboratory is often a difficult course for students in terms of translating the structural information and reactivity learned in lecture to the practical applications found in the laboratory. These concepts are even more difficult when presented through distance learning when a student cannot get hands-on experience.…

An undergraduate laboratory experiment for the synthesis of biologically significant bis-4-hydroxycoumarins using a new catalyst is described here. An experimental setup plan, monitoring the reaction by TLC, isolation of the product, safe laboratory handling procedures, and significance of data reproducibility of the result are the main learning…

This study investigated Chemistry students' performance and retention (knowledge and understanding, knowledge and application, perception and attitude) in Organic Chemistry in three Senior High Schools (SHSs) within Tamale Metropolis in Ghana. Collaborative learning models were employed as intervention strategies. Quasi-experimental design was…

Undergraduate chemistry laboratory instruction can be considered from many perspectives and addresses multiple educational aims. We critically assess an inventory of "Cognitive Tasks of Experimental Research" for its applicability to chemistry laboratory teaching, and then apply it to an integrated upper-level laboratory course as an…

Organic reaction trajectories show atomic motion and molecular reorganization of reactants during a single product-forming collision. iORA is a free (available from the Apple App Store), easy to use, highly interactive iPhone application that provides on-the-fly 3Drendering of organic reaction trajectories calculated with density functional theory…

This article reports the development of Chem'Sc@pe, an escape game activity for first- and second-year undergraduate students, covering various topics from an introductory organic chemistry course. The objective was to encourage them to review notions learned in class in a fun and collaborative environment. The set comprises a game board…

Different molecular representations are usually used to depict the three-dimensional (3D) structure of organic compounds. Mastering the skill of interconverting one form into another is essential for students to ensure success in organic chemistry. The traditional and recently developed methods for completing such interconversions that rely on 3D…