The purpose of this research was to establish a case for the use of serious simulation games as a tool to enhance the learning of sales leadership skills. The study provides taxonomy around serious simulation games as a specific modality at the intersection of serious games and simulation games, which have a focus toward education. A literature review was used to build a research model to explain the factors that contribute to the effectiveness of an SSG deployed in a sales leadership program. In order to test the efficacy of this model, a sales leadership SSG was built for a sales leadership academic program. This SSG was built based on experience developing other programs, one specifically was a manufacturing game developed for Dana corporation. The research model was tested using a survey instrument, which was developed as the sales leadership SSG was being built. This instrument was used to collect self-reported responses from the students in the sales leadership course, which measured the factors around the efficacy of the SSG in this program. 166 students responded to the survey over five (5) semesters, and were analyzed using factor analysis and regression. The results demonstrated the efficacy of the theory, and supported 6 out of 7 of the hypotheses. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]