Autism spectrum disorders (ASDs) are a group of neurodevelopmental-related disorders with a high genetic risk. Recently, chromatin remodeling factors have been found to be related to ASDs. "SMARCA4" is such a catalytic subunit of the chromatin-remodeling complex. In this report, we identified seven novel missense variants in the…

Background: Supporting participation in decision making is complex, dynamic and multifactorial. The aim of this study was to understand more about the difficulties parents of adults with intellectual disabilities experienced in providing decision support and their strategies for resolving them. Method: Participants were 23 parents who regularly…

This article explores the role of formal and informal supports for women with intellectual and developmental disabilities (IDD) throughout their pregnancy, childbirth, and postpartum experiences. Data from qualitative interviews with women with IDD (n = 16) were analyzed. Results showed that formal supports aided in planning, transportation,…

Background: This study is inclusive research. Inclusive research is when people with disability are involved as researchers. The aim of this project was to focus on relationships that people with intellectual disability have and to find what makes these relationships work. Another aim of this project was to share stories about these relationships…

Background: Reducing hospital admissions for people with a learning disability is a key objective of national guidelines. However, there are currently little available data which indicate factors which might reduce the risk of hospital admission. Using a cohort of people at risk of hospital admission, this research sought to explore the…

Polypharmacy is a risk factor for drug interactions (DI). Adults with intellectual and developmental disabilities (IDD) are at increased risk for polypharmacy and as such increased risk for potential DIs. The objectives of this study were to determine the number of potential DIs present in medication regimens of adults with IDD as well as factors…

Background: People with intellectual disability may be at elevated risk of adverse consequences of substance use. This study outlines the prevalence of, and factors associated with, substance use in young people with and without intellectual disability. Method: Secondary analysis was undertaken of the Next Steps annual panel study, which follows a…

Background: The aim of this study was to explore and describe access to the Internet and how it is used among adolescents and young adults with mild and moderate intellectual disabilities in their everyday settings. Method: Data were collected through observations of and interviews with 15 participants with intellectual disabilities, aged 13-25…

This paper criticizes mainstream philosophical justifications for paternalism in children's education, highlighting their exclusion of students labelled with intellectual disability. Most philosophical justifications of paternalism presume "able-mindedness" -- that is, they presume that learners possess the potential to develop…

Background: Mobile technology has the potential to assist adults with intellectual disabilities to initiate and maintain social connections in important areas of their lives, such as family, friends and work/volunteering. Method: The present study investigated how specific aspects of mobile device/app use are associated with the social inclusion…

Background: Adults with intellectual and developmental disabilities and their families have high need for support services. This study assessed resource utilization among caregivers of intellectual and developmental disabilities and other conditions. Methods: We assessed 366 caregivers of adults with intellectual and developmental disabilities,…

Background: Health professionals were trained to deliver adapted psychological interventions for depression to people with learning disabilities and depression alongside a supporter. Exploring the delivery of psychological interventions can help increase access to therapy. Method: Twenty-seven participants took part in six focus groups, and the…

Objectives: The main objective was to identify the test-retest reliability of the Wii Balance Board (WBB) for assessing standing balance when administered to a population of people with intellectual disability (ID). A secondary objective was to provide information regarding the reliability of the WBB, taking into account the severity of cognitive…

Background: It can be challenging for people with intellectual disabilities to convey their thoughts and opinions because of cognitive, speech and language impairments. Consequently, facilitating their ability to communicate using augmentative and alternative communication methods is essential. The picture-based framework Talking Mats has been…

Background: Interactive engagement, specifically attention and initiation, are considered important skills for facilitating development and learning in students with severe/profound intellectual and multiple disabilities. Prior research has suggested that music therapy and multisensory storytelling are two promising interventions for supporting…