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Vergne, Matthew J. – Journal of Chemical Education, 2021
This laboratory experiment introduces upper-division undergraduate analytical chemistry students to liquid chromatography-tandem mass spectrometry (LC-MS/MS) in a forensic application: the analysis of cocaine and metabolites of cocaine in simulated serum ostensibly from drug overdose victims. For this investigation, students developed the…
Descriptors: Science Experiments, Science Laboratories, Laboratory Experiments, Undergraduate Students
Cole, Charles La Von, III – ProQuest LLC, 2019
This comparative case study utilized oral histories to illuminate the life stories of three Black men who navigated their way through trauma. The goal of the study was to better understand how they navigated education and life experiences to eventually earn doctoral degrees. The findings affirm and illuminate that despite their academic success,…
Descriptors: African Americans, Males, Doctoral Degrees, Trauma
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Wolter, Michael; Huff, Ethan; Speigel, Talia; Winters, Boyer D.; Leri, Francesco – Learning & Memory, 2019
To test the hypothesis that drugs of abuse and their conditioned stimuli (CSs) enhance memory consolidation, the effects of post-training exposure to cocaine and nicotine were compared to the effects of post-training exposure to contextual stimuli that were paired with the effects of these drugs. Using the object recognition (OR) task, it was…
Descriptors: Cocaine, Smoking, Substance Abuse, Recognition (Psychology)
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Liu, Yiyang; Ball, Jacob D.; Elliott, Amy L.; Jacobs-Elliott, Michelle; Nicolette, Guy – Journal of American College Health, 2020
Objective: Cocaine use is increasing. Comorbidities and diagnostic sequencing are needed among college students to inform treatment of cocaine use disorder (CUD). Method: Using electronic medical records from the psychiatric clinic at the student health care center of a large, public university from 2005 to 2015, patients diagnosed with CUD were…
Descriptors: Cocaine, Drug Abuse, Mental Disorders, College Students
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Jeynes, William H. – Education and Urban Society, 2022
The meta-analysis, that included 75 studies, examined the relationship between illegal drug consumption, on the one hand, and student academic and behavioral outcomes, on the other, for the middle school to college grade levels. The meta-analysis first (research question #1) addressed whether there is a statistically significant relationship…
Descriptors: Middle School Students, High School Students, College Students, Drug Use
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Doncheck, Elizabeth M.; Hafenbreidel, Madalyn; Ruder, Sarah A.; Fitzgerald, Michael K.; Torres, Lilith; Mueller, Devin – Learning & Memory, 2018
In cocaine use disorder, relapse can be elicited by drug-associated cues despite long periods of abstinence. The persistence of drug-associated cues in eliciting drug seeking suggests enduring changes in structural and functional plasticity, which may be mediated by basic fibroblast growth factor (bFGF, FGF2). Stimulant drug use increases bFGF…
Descriptors: Cocaine, Cues, Drug Use, Rewards
Patrick, Megan E.; Schulenberg, John E.; Miech, Richard A.; Johnston, Lloyd D.; O'Malley, Patrick M.; Bachman, Jerald G. – Institute for Social Research, 2022
This volume presents new 2021 findings from the U.S. national Monitoring the Future follow-up (panel) study concerning substance use among the nation's college students and adults from ages 19 through 60. We report 2021 prevalence estimates on numerous illicit and licit substances, examine how substance use differs across this age span, and show…
Descriptors: Substance Abuse, College Students, Adults, Incidence
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Filges, Trine; Andersen, Ditte; Jørgensen, Anne-Marie Klint – Research on Social Work Practice, 2018
Objectives: This review evaluates the evidence on the effects of functional family therapy (FFT) on drug abuse reduction for young people in treatment for nonopioid drug use. Data and Analysis: We followed Campbell Collaboration guidelines to conduct a systematic review of randomized and nonrandomized trials. Results: The search yielded two…
Descriptors: Family Counseling, Therapy, Drug Abuse, Youth
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Marshall, Andrew T.; Ostlund, Sean B. – Learning & Memory, 2018
Drug-paired cues acquire powerful motivational properties, but only lead to active drug-seeking behavior if they are potent enough to overwhelm the cognitive control processes that serve to suppress such urges. Studies using the Pavlovian-to-instrumental transfer (PIT) task have shown that rats pretreated with cocaine or amphetamine exhibit…
Descriptors: Cues, Drug Use, Animals, Delay of Gratification
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Briggs, Sherri B.; Blouin, Ashley M.; Young, Erica J.; Rumbaugh, Gavin; Miller, Courtney A. – Learning & Memory, 2017
Depolymerizing actin in the amygdala through nonmuscle myosin II inhibition (NMIIi) produces a selective, lasting, and retrieval-independent disruption of the storage of methamphetamine-associated memories. Here we report a similar disruption of memories associated with amphetamine, but not cocaine or morphine, by NMIIi. Reconsolidation appeared…
Descriptors: Memory, Brain Hemisphere Functions, Brain, Inhibition
Curtin, Sally C.; Tejada-Vera, Betzaida; Warner, Margaret – National Center for Health Statistics, 2017
Drug overdose deaths in the United States are a pressing public health challenge. In particular, drug overdoses involving opioids have increased since 1999. This report focuses specifically on drug overdose deaths for older adolescents aged 15-19. In 2015, 772 drug overdose deaths occurred in this age group. Rates for 1999-2015 are presented and…
Descriptors: Drug Abuse, Death, Late Adolescents, Gender Differences
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Pizzimenti, Christie L.; Navis, Tom M.; Lattal, K. Matthew – Learning & Memory, 2017
Even following long periods of abstinence, individuals with anxiety disorders have high rates of relapse to drugs of abuse. Although many current models of relapse demonstrate effects of acute stress on drug-seeking, most of these studies examine stressful experiences that occur in close temporal and physical proximity to the reinstatement test.…
Descriptors: Anxiety Disorders, Drug Addiction, Posttraumatic Stress Disorder, Fear
Johnston, Lloyd D.; Miech, Richard A.; O'Malley, Patrick M.; Bachman, Jerald G.; Schulenberg, John E.; Patrick, Megan E. – Institute for Social Research, 2022
Monitoring the Future (MTF) is a long term study of substance use and related factors among U.S. adolescents, college students, and adult high school graduates through age 60. It is conducted annually and supported by the National Institute on Drug Abuse. MTF findings identify emerging substance use problems, track substance use trends, are…
Descriptors: Substance Abuse, Adolescents, COVID-19, Pandemics
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Doucette, Alan Austin; Chisholm, Roderick A. – Journal of Chemical Education, 2019
Mass spectrometry is frequently introduced to undergraduate students as an instrument for both qualitative and quantitative chemical analysis. One of the most common uses of mass spectrometry (MS) is to deduce or confirm a compound's chemical formula, by relying on high-resolution accurate-mass measurements. However, like all forms of instrumental…
Descriptors: Undergraduate Students, College Science, Inquiry, Active Learning
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Parker, Patrick D.; Beers, Brandon; Vergne, Matthew J. – Journal of Chemical Education, 2017
Laboratory experiments were developed to introduce students to the quantitation of drugs of abuse by high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Undergraduate students were introduced to internal standard quantitation and the LC-MS/MS method optimization for cocaine. Cocaine extracted from paper currency was…
Descriptors: Undergraduate Students, Chemistry, Laboratory Experiments, Cocaine
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