Children with complex and severe communication impairments often cannot meet their communication needs with their natural voice and may require the use of augmentative and alternative communication (AAC). There are many communication and learning challenges facing children who use AAC; however, using AAC for social communication is especially difficult. Although several options are available to target social communication, providing peers with knowledge and skills on how to interact with children who use AAC has produced positive results. Four themes have emerged from the literature that provides a framework for implementing peer intervention within a classroom-based service delivery model: (a) increase knowledge of multimodal communication; (b) increase knowledge of AAC systems; (c) develop an understanding of the barriers of AAC communication, and (d) develop proficiency of appropriate interaction skills. Presented in this article are a variety of classroom-based activities to improve the social competence of peers and students who use AAC. (Contains 4 figures.)