Art therapy has been used to support the coping skills of patients with various medical illnesses. The purpose of this case study was to examine the usefulness of art therapy in promoting communication and a positive sense of well-being in a hemodialysis patient. The participant was a 57-year-old Caucasian female who had been treated with hemodialysis for the past 3 years. Two art therapy sessions per week were provided for 4 weeks. The participant was able to express enjoyment with her artistic expressions and challenge herself to learn something new. Following completion of art therapy, the participant indicated a feeling of accomplishment and an increased sense of control and self-confidence. Although these results cannot be generalized, they are worthy of further investigation. Thus, application of art therapy with other hemodialysis patients is recommended.