The ability of organizations to adapt quickly to change and take action in uncertain situations brought about by a crisis or change is vital for their development and continuity. Teachers, who are education workers, form the basis of the education system by producing education services. Therefore, the power of the education system to take action against uncertainties is determined by whether teachers take action in the face of uncertainties. The purpose of this study is to look into the impact of teachers' perceptions of organizational uncertainty on organizational inertia. An explanatory and predictive pattern, one of the correlational research designs, was used in the study. The study sample consists of 307 teachers, determined by a simple random sampling method from the teachers working in the Eyüp District of Istanbul. Organizational Inertia Scale and Organizational Uncertainty Scale were used as data collection tools. As a result of the research, it was seen that there were significant differences in the perception of inertia and organizational uncertainty according to the demographic characteristics of the teachers. However, it was concluded that teachers' perceptions of organizational uncertainty predicted their inertia attitudes.