Disruptive students potentially pose significant problems for campus administrators as they strive to maintain a safe campus environment conducive to learning while not violating the legal rights of the students. Maintaining a safe campus is important because increasing numbers of students with mental and cognitive disorders are enrolling in college and university classes. This article examines selected court cases involving disruptive students who alleged violations of their First Amendment right of free speech, due process rights under the Fourteenth Amendment, and violations of the rights afforded them under the Americans with Disabilities Act and the Rehabilitation Act. The rulings in these cases were used to develop campus guidelines and procedures to address the actions of disruptive students.