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Showing 31 to 45 of 161 results Save | Export
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Jin, Iksung; Kandel, Eric R.; Hawkins, Robert D. – Learning & Memory, 2011
Whereas short-term plasticity involves covalent modifications that are generally restricted to either presynaptic or postsynaptic structures, long-term plasticity involves the growth of new synapses, which by its nature involves both pre- and postsynaptic alterations. In addition, an intermediate-term stage of plasticity has been identified that…
Descriptors: Animals, Biochemistry, Neurological Organization
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Palombi, Peggy Shadduck; Jagger, Kathleen Snell – Bioscene: Journal of College Biology Teaching, 2008
Using cultured fibroblast cells, undergraduate students explore cell division and the responses of cultured cells to a variety of environmental changes. The students learn new research techniques and carry out a self-designed experiment. Through this project, students enhance their creative approach to scientific inquiry, learn time-management and…
Descriptors: Undergraduate Students, Student Attitudes, Cytology, Inquiry
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Hancock, Dale; Funnell, Alister; Jack, Briony; Johnston, Jill – Biochemistry and Molecular Biology Education, 2010
An experiment is conducted, which in four 3 h laboratory sessions, introduces third year undergraduate Biochemistry students to the technique of real-time PCR in a biological context. The model used is a murine erythroleukemia cell line (MEL cells). These continuously cycling, immature red blood cells, arrested at an early stage in erythropoiesis,…
Descriptors: Undergraduate Students, Genetics, Cytology, Biochemistry
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Lewis, Jennifer R.; Kotur, Mark S.; Butt, Omar; Kulcarni, Sumant; Riley, Alyssa A.; Ferrell, Nick; Sullivan, Kathryn D.; Ferrari, Mauro – Cell Biology Education, 2002
The purpose of this article is to discuss "small-group apprenticeships (SGAs)" as a method to instruct cell culture techniques to high school participants. The study aimed to teach cell culture practices and to introduce advanced imaging techniques to solve various biomedical engineering problems. Participants designed and completed experiments…
Descriptors: Science Instruction, Secondary School Science, High School Students, Science Experiments
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Hammamieh, Rasha; Anderson, Margery; Carr, Katharine; Tran, Christine N.; Yourick, Debra L.; Jett, Marti – Cell Biology Education, 2005
The potential for personalized cancer management has long intrigued experienced researchers as well as the naive student intern. Personalized cancer treatments based on a tumor's genetic profile are now feasible and can reveal both the cells' susceptibility and resistance to chemotherapeutic agents. In a weeklong laboratory investigation that…
Descriptors: Cancer, Oncology, Molecular Biology, Drug Therapy
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Neumann, Manuela; Bentmann, Eva; Dormann, Dorothee; Jawaid, Ali; DeJesus-Hernandez, Mariely; Ansorge, Olaf; Roeber, Sigrun; Kretzschmar, Hans A.; Munoz, David G.; Kusaka, Hirofumi; Yokota, Osamu; Ang, Lee-Cyn; Bilbao, Juan; Rademakers, Rosa; Haass, Christian; Mackenzie, Ian R. A. – Brain, 2011
Accumulation of the DNA/RNA binding protein fused in sarcoma as cytoplasmic inclusions in neurons and glial cells is the pathological hallmark of all patients with amyotrophic lateral sclerosis with mutations in "FUS" as well as in several subtypes of frontotemporal lobar degeneration, which are not associated with "FUS" mutations. The mechanisms…
Descriptors: Cancer, Pathology, Patients, Genetics
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2009
The "fos" proto-oncogene codes for a component of the AP1 transcription factor, an important regulator of gene expression and cell proliferation. Dysregulation of AP1 function may lead to the malignant transformation of the cell. The present test describes an experiment in which the role of a micro-RNA (miR-7b) in the regulation of "fos" gene…
Descriptors: Genetics, Cancer, Role, Molecular Biology
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Woloschak, Gayle; And Others – Science Teacher, 1995
Describes experiments to culture cells in a laboratory that provide students with hands-on experience in manipulating cells and a chance to observe cell growth characteristics first hand. Exposes students to sterile technique, cell culture, cell growth concepts, and eukaryotic cell structure. (JRH)
Descriptors: Cytology, Hands on Science, Science Activities, Science Education
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Aucoin, Marc G.; Jolicoeur, Mario – Chemical Engineering Education, 2009
Undergraduate and graduate engineering training differ significantly. The former looks to established protocols and formulas to design and control processes while the latter often involves questioning established protocols and formulas to better suit and describe phenomena. Although we do not dispute the benefits of practical hands-on approaches,…
Descriptors: Engineering Education, Graduate Students, Research Problems, Research Design
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Chang, Bo – International Journal of Lifelong Education, 2010
Knowledge construction is regarded as an effective learning model in practice. When more and more learning communities are organized to promote knowledge construction, it is necessary to know how to use different tools to support knowledge construction in the learning community context. In the literature, few researchers discuss how to construct…
Descriptors: Constructivism (Learning), Open Education, Foreign Countries, Cooperative Learning
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Moss, Robert; Solomon, Sondra – American Biology Teacher, 1991
A tissue culture experiment that does not require elaborate equipment and that can be used to teach sterile technique, the principles of animal cell line maintenance, and the concept of cell growth curves is described. The differences between cancerous and normal cells can be highlighted. The procedure is included. (KR)
Descriptors: Animals, Biology, Culturing Techniques, Cytology
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Coras, Roland; Siebzehnrubl, Florian A.; Pauli, Elisabeth; Huttner, Hagen B.; Njunting, Marleisje; Kobow, Katja; Villmann, Carmen; Hahnen, Eric; Neuhuber, Winfried; Weigel, Daniel; Buchfelder, Michael; Stefan, Hermann; Beck, Heinz; Steindler, Dennis A.; Blumcke, Ingmar – Brain, 2010
The hippocampal dentate gyrus maintains its capacity to generate new neurons throughout life. In animal models, hippocampal neurogenesis is increased by cognitive tasks, and experimental ablation of neurogenesis disrupts specific modalities of learning and memory. In humans, the impact of neurogenesis on cognition remains unclear. Here, we…
Descriptors: Surgery, Patients, Memory, Cognitive Ability
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Surratt, Christopher K.; Witt-Enderby, Paula A.; Johnson, David A.; Anderson, Carl A.; Bricker, J. Douglas; Davis, Vicki L.; Firestine, Steven M.; Meng, Wilson S. – CBE - Life Sciences Education, 2006
To provide graduate students in pharmacology/toxicology exposure to, and cross-training in, a variety of relevant laboratory skills, the Duquesne University School of Pharmacy developed a "methods" course as part of the core curriculum. Because some of the participating departmental faculty are neuroscientists, this course often applied…
Descriptors: Graduate Students, Research Design, Core Curriculum, Laboratory Schools
Nester, Bradley S.; Turney, Tully H. – Collegiate Microcomputer, 1992
Describes the use of a Macintosh computer and HyperCard software to create an introduction to cell culture techniques that closely approximates a hands-on laboratory experiment. Highlights include data acquisition, data analysis, the generation of growth curves, and electronic modeling. (LRW)
Descriptors: Biology, Computer Assisted Instruction, Computer Simulation, Courseware
Phaff, Herman J. – Scientific American, 1981
Describes industrially important yeasts, molds, bacteria, and actinomycetes. Discussed in detail are microbial products, such as primary metabolites, secondary metabolites, enzymes, and capsular polysaccharides. Traces the historical background of human cell culture, mentioning recombinant DNA research and hybridization of normal mammalian cells…
Descriptors: Biochemistry, Biological Sciences, Chemical Industry, College Science
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