ERIC Number: EJ1073029
Record Type: Journal
Publication Date: 2015-Sep
Abstractor: As Provided
Are Autistic Traits in the General Population Related to Global and Regional Brain Differences?
Koolschijn, P. Cédric M. P.; Geurts, Hilde M.; van der Leij, Andries R.; Scholte, H. Steven
Journal of Autism and Developmental Disorders, v45 n9 p2779-2791 Sep 2015
There is accumulating evidence that autistic-related traits in the general population lie on a continuum, with autism spectrum disorders representing the extreme end of this distribution. Here, we tested the hypothesis of a possible relationship between autistic traits and brain morphometry in the general population. Participants completed the short autism-spectrum quotient-questionnaire (AQ); T1-anatomical and DWI-scans were acquired. Associations between autistic traits and gray matter, and white matter microstructural-integrity were performed on the exploration-group (N = 204; 105 males, M-age = 22.85), and validated in the validation-group (N = 304; 155 males, M-age = 22.82). No significant associations were found between AQ-scores and brain morphometry in the exploration-group, or after pooling the data. This questions the assumption that autistic traits and their morphological associations do lie on a continuum in the general population.
Descriptors: Autism, Symptoms (Individual Disorders), Pervasive Developmental Disorders, Hypothesis Testing, Correlation, Brain Hemisphere Functions, Questionnaires, Diagnostic Tests, Scores, Foreign Countries
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Location: Netherlands