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Showing 1 to 15 of 193 results Save | Export
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Simpson, Scott; Izydorczak, Alexandra M. – Journal of Chemical Education, 2018
Students in an upper-level physical chemistry course used a polarimeter to measure the molar optical rotation of different optically active amino acids to confirm the Clough, Lutz, and Jirgensons (CLJ) rule. This rule states that an amino acid is in the l-configuration if the molar optical rotation becomes more positive upon the addition of acid…
Descriptors: Chemistry, Measurement, Motion, Optics
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Pennington, Britney O.; Sears, Duane; Clegg, Dennis O. – Biochemistry and Molecular Biology Education, 2014
We developed an interactive exercise to teach students how to draw the structures of the 20 standard amino acids and to identify the one-letter abbreviations by modifying the familiar game of "Hangman." Amino acid structures were used to represent single letters throughout the game. To provide additional practice in identifying…
Descriptors: Chemistry, Educational Games, Memory, Pretests Posttests
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Sims, Paul A. – Journal of Chemical Education, 2011
Learning the 20 standard amino acids is an essential component of an introductory course in biochemistry. Later in the course, the students study metabolism and learn about various catabolic and anabolic pathways involving amino acids. Learning new material or concepts often is easier if one can connect the new material to what one already knows;…
Descriptors: Introductory Courses, Biochemistry, Puzzles, Metabolism
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Simpson, Scott; Autschbach, Jochen; Zurek, Eva – Journal of Chemical Education, 2013
A computational experiment that investigates the optical activity of the amino acid valine has been developed for an upper-level undergraduate physical chemistry laboratory course. Hybrid density functional theory calculations were carried out for valine to confirm the rule that adding a strong acid to a solution of an amino acid in the l…
Descriptors: Science Instruction, Chemistry, College Science, Undergraduate Study
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Gonzalez, Elizabeth; Dolino, Drew; Schwartzenburg, Danielle; Steiger, Michelle A. – Journal of Chemical Education, 2015
A laboratory experiment was developed to introduce students in either an organic chemistry or biochemistry lab course to two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy using simple biomolecules. The goal of this experiment is for students to understand and interpret the information provided by a 2D NMR spectrum. Students are…
Descriptors: Science Instruction, Biochemistry, Organic Chemistry, Science Laboratories
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Halmo, Stephanie M.; Sensibaugh, Cheryl A.; Bhatia, Kush S.; Howell, Alexandra; Ferryanto, Ersta P.; Choe, Bryant; Kehoe, Kaitlin; Watson, Morgan; Lemons, Paula P. – Biochemistry and Molecular Biology Education, 2018
Protein structure-function is a key concept in biochemistry. We used the perspective of domain-specific problem-solving to investigate students' solutions to a well-defined protein structure-function problem. We conducted think-aloud interviews with 13 undergraduate students and performed qualitative content analysis to examine the differences in…
Descriptors: Biochemistry, Problem Solving, Science Process Skills, Molecular Structure
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Reißer, Sabine; Prock, Sebastian; Heinzmann, Hartmut; Ulrich, Anne S. – Biochemistry and Molecular Biology Education, 2018
Protein ORIGAMI (http://ibg.kit.edu/protein_origami) is a browser-based web application that allows the user to create straightforward 3D paper models of folded peptides for research, teaching and presentations. An amino acid sequence can be turned into a-helices, ß-strands and random coils that can be printed out and folded into properly scaled…
Descriptors: Educational Technology, Technology Uses in Education, Models, Science Instruction
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Lin, Henry J.; Lehoang, Jennifer; Kwan, Isabel; Baghaee, Anita; Prasad, Priya; Ha-Chen, Stephanie J.; Moss, Tanesha; Woods, Jeremy D. – Biochemistry and Molecular Biology Education, 2018
The 8 studs on a 2 × 4 Lego brick conveniently represent the outer shell of electrons for carbon, nitrogen, and oxygen atoms. We used Lego bricks to model these atoms, which are then joined together to form molecules by following the Lewis octet rule. A variety of small biological molecules can be modeled in this way, such as most amino acids,…
Descriptors: Toys, Molecular Biology, Science Instruction, Teaching Methods
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Kean, Kelsey M.; van Zee, Kari; Mehl, Ryan A. – Journal of Chemical Education, 2019
The content and design scheme for a readily adaptable, research-based laboratory course in chemical biology are presented. In this course, students interrogate protein structure and function using the site-specific incorporation of noncanonical amino acids by genetic code expansion. The relatively new field of genetic code expansion enables…
Descriptors: Science Instruction, Biochemistry, Science Laboratories, Genetics
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Crowther, Gregory J.; Davis, Katie – Journal of Chemical Education, 2013
Music is not typically used in teaching high school- and college-level chemistry. This may be attributable to instructors' perceptions of educational music as being solely for memorization, their uncertainty about how to incorporate music effectively, or because of a limited number of suitable songs in which the music and words reinforce each…
Descriptors: Teaching Methods, Music Activities, Secondary School Science, High Schools
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Reed, Kelynne E.; Richardson, John M. – Biochemistry and Molecular Biology Education, 2013
We used the Integrated Microbial Genomes Annotation Collaboration Toolkit as a framework to incorporate microbial genomics research into a microbiology and biochemistry course in a way that promoted student learning of bioinformatics and research skills and emphasized teamwork and collaboration as evidenced through multiple assessment mechanisms.…
Descriptors: Genetics, Documentation, Microbiology, Biochemistry
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Cai, Longfei; Wu, Yunying; Xu, Chunxiu; Chen, Zefeng – Journal of Chemical Education, 2013
An experiment was developed to demonstrate a microfluidic device in the analytical chemistry (instrumental analysis) laboratory. Students made the paper-based microfluidic device with a wax pen and a piece of filter paper and used it to determine the total quantity of amino acids in a green tea leaf extract. The device is low cost, easy-to-make,…
Descriptors: Chemistry, Science Experiments, College Science, Science Laboratories
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Maza, Johnathan C.; Villa, Jordan K.; Landino, Lisa M.; Young, Douglas D – Journal of Chemical Education, 2016
The site-specific introduction of unnatural amino acids (UAAs) has been demonstrated to be a useful tool in protein engineering. Moreover, the incorporation of a UAA into a protein has become feasible with the increased commercial availability of UAAs and robust expression plasmids. In addition to the ease of incorporation, the concepts utilized…
Descriptors: Undergraduate Students, Biochemistry, Science Experiments, Science Instruction
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Yeo, Brandon Pei Hui; Foong, Lian Chee; Tam, Sheh May; Lee, Vivian; Hwang, Siaw San – Biochemistry and Molecular Biology Education, 2018
Structures and functions of protein motifs are widely included in many biology-based course syllabi. However, little emphasis is placed to link this knowledge to applications in biotechnology to enhance the learning experience. Here, the conserved motifs of nucleotide binding site-leucine rich repeats (NBS-LRR) proteins, successfully used for the…
Descriptors: Genetics, Science Instruction, Teaching Methods, Biochemistry
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Meyer, Scott C. – Journal of Chemical Education, 2015
An upper-division undergraduate laboratory experiment is described that explores the structure/function relationship of protein domains, namely leucine zippers, through a molecular graphics computer program and physical models fabricated by 3D printing. By generating solvent accessible surfaces and color-coding hydrophobic, basic, and acidic amino…
Descriptors: College Science, Undergraduate Study, Science Laboratories, Science Experiments
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