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Showing 1 to 15 of 208 results Save | Export
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Šarac, Bojan; Hadži, San – Journal of Chemical Education, 2021
A Microsoft Excel workbook has been developed to simplify the quantitative analysis of experimentally measured titration curves for diprotic and triprotic amino acids such as glycine, arginine, histidine, and glutamate. Students perform the titration, enter the data into the worksheet, and manually adjust the resulting pK[subscript a] values to…
Descriptors: Science Instruction, College Science, Undergraduate Study, Spreadsheets
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Novak, Igor – Biochemistry and Molecular Biology Education, 2021
Ionization of amino acids (AA) is very important concept in biochemistry. We integrate the mathematical concept of probability with biochemically relevant process of AA ionization. We visualize the ionization process with Mathematica software discussing intramolecular interactions between weakly acidic/basic functional groups and charge--pH…
Descriptors: Biochemistry, Scientific Concepts, Visualization, Probability
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Simpson, Scott; Izydorczak, Alexandra M. – Journal of Chemical Education, 2018
Students in an upper-level physical chemistry course used a polarimeter to measure the molar optical rotation of different optically active amino acids to confirm the Clough, Lutz, and Jirgensons (CLJ) rule. This rule states that an amino acid is in the l-configuration if the molar optical rotation becomes more positive upon the addition of acid…
Descriptors: Chemistry, Measurement, Motion, Optics
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Roncevic, Tamara N.; Sedlar, Agneš; Rodic, Dušica D.; Segedinac, Mirjana D. – Biochemistry and Molecular Biology Education, 2019
In this study, a set of hybrid images was designed as a new and up-to-date unexamined type of external visual representations in the chemistry classroom. One challenging teaching theme was chosen ("Amino acids and proteins"), and the hybrid images were used among novices--primary school students. For the purpose of the study, two groups…
Descriptors: Elementary School Science, Elementary School Students, Science Instruction, Chemistry
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Dounay, Amy B.; O'Donnell, Martin J.; Samaritoni, J. Geno; Popiolek, Lukasz; Schirch, Douglas; Biernasiuk, Anna; Malm, Anna; Lamb, Isaac W.; Mudrack, Kristen; Rivera, Daniel G.; Ojeda, Gerardo M.; Scott, William L. – Journal of Chemical Education, 2019
An experiment for the synthesis of N-acyl derivatives of natural amino acids has been developed as part of the Distributed Drug Discovery (D3) program. Students use solid-phase synthesis techniques to complete a three-step, combinatorial synthesis of six products, which are analyzed using LC-MS and NMR spectroscopy. This protocol is suitable for…
Descriptors: Organic Chemistry, Laboratory Experiments, Science Experiments, Pharmacology
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Sims, Paul A. – Journal of Chemical Education, 2011
Learning the 20 standard amino acids is an essential component of an introductory course in biochemistry. Later in the course, the students study metabolism and learn about various catabolic and anabolic pathways involving amino acids. Learning new material or concepts often is easier if one can connect the new material to what one already knows;…
Descriptors: Introductory Courses, Biochemistry, Puzzles, Metabolism
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Pennington, Britney O.; Sears, Duane; Clegg, Dennis O. – Biochemistry and Molecular Biology Education, 2014
We developed an interactive exercise to teach students how to draw the structures of the 20 standard amino acids and to identify the one-letter abbreviations by modifying the familiar game of "Hangman." Amino acid structures were used to represent single letters throughout the game. To provide additional practice in identifying…
Descriptors: Chemistry, Educational Games, Memory, Pretests Posttests
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Acan, Sinan Can; Acan, Naciye Leyla – Biochemistry and Molecular Biology Education, 2019
Recently, manuscripts that use bioinformatics tools to convert proteins and other biological materials into music have appeared in several journals. The authors claim that this type of studies adds joy to education of life sciences and attract public attention to biochemistry education along with other uses. We thought the reverse of the process…
Descriptors: Molecular Biology, Information Science, Biochemistry, Music
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Panjwani, Anita A.; Ji, Yuelong; Fahey, Jed W.; Palmer, Amanda; Wang, Guoying; Hong, Xiumei; Zuckerman, Barry; Wang, Xiaobin – Journal of Autism and Developmental Disorders, 2020
In contrast to the well-observed associations between obesity, diabetes, and autism spectrum disorder (ASD), the roles of maternal dyslipidemia and sex disparity in ASD have not been well-studied. We examined the joint associations of maternal plasma cholesterols, branched-chain amino acids (BCAAs) and child sex on child ASD risk. We analyzed data…
Descriptors: Obesity, Diabetes, Autism, Pervasive Developmental Disorders
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Simpson, Scott; Autschbach, Jochen; Zurek, Eva – Journal of Chemical Education, 2013
A computational experiment that investigates the optical activity of the amino acid valine has been developed for an upper-level undergraduate physical chemistry laboratory course. Hybrid density functional theory calculations were carried out for valine to confirm the rule that adding a strong acid to a solution of an amino acid in the l…
Descriptors: Science Instruction, Chemistry, College Science, Undergraduate Study
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Kerwin, Sean M. – Biochemistry and Molecular Biology Education, 2019
A flexible and modular peptide modeling set was designed using freely available software tools. The set consists of space-filling models of all 20 naturally occurring amino acid side chains and a modular kit for constructing peptides employing C-alpha carbons and amide bond groups. Connectors that allow free rotation about phi and psi angles on…
Descriptors: Computer Software, Teaching Methods, Science Instruction, Computer Peripherals
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Halmo, Stephanie M.; Sensibaugh, Cheryl A.; Bhatia, Kush S.; Howell, Alexandra; Ferryanto, Ersta P.; Choe, Bryant; Kehoe, Kaitlin; Watson, Morgan; Lemons, Paula P. – Biochemistry and Molecular Biology Education, 2018
Protein structure-function is a key concept in biochemistry. We used the perspective of domain-specific problem-solving to investigate students' solutions to a well-defined protein structure-function problem. We conducted think-aloud interviews with 13 undergraduate students and performed qualitative content analysis to examine the differences in…
Descriptors: Biochemistry, Problem Solving, Science Process Skills, Molecular Structure
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Nikam, Vidya; Ranade, Suvidya; Shaik Mohammad, Naushad; Kulkarni, Mohan – International Journal of Developmental Disabilities, 2021
Intellectual disability (ID) is a neurodevelopmental disorder characterized by cognitive delays. Inborn errors of metabolism constitute an important subgroup of ID for which various treatments options are available. We aimed to identify potential biomarkers of inherited metabolic disorders from the children with ID using tandem mass spectrometry…
Descriptors: Intellectual Disability, Biochemistry, Metabolism, At Risk Persons
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Gonzalez, Elizabeth; Dolino, Drew; Schwartzenburg, Danielle; Steiger, Michelle A. – Journal of Chemical Education, 2015
A laboratory experiment was developed to introduce students in either an organic chemistry or biochemistry lab course to two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy using simple biomolecules. The goal of this experiment is for students to understand and interpret the information provided by a 2D NMR spectrum. Students are…
Descriptors: Science Instruction, Biochemistry, Organic Chemistry, Science Laboratories
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Reißer, Sabine; Prock, Sebastian; Heinzmann, Hartmut; Ulrich, Anne S. – Biochemistry and Molecular Biology Education, 2018
Protein ORIGAMI (http://ibg.kit.edu/protein_origami) is a browser-based web application that allows the user to create straightforward 3D paper models of folded peptides for research, teaching and presentations. An amino acid sequence can be turned into a-helices, ß-strands and random coils that can be printed out and folded into properly scaled…
Descriptors: Educational Technology, Technology Uses in Education, Models, Science Instruction
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