This study represents a research validating the efficacy of Davis' Technology Acceptance Model (TAM) by pairing it with the Organizational Change Readiness Theory (OCRT) to develop another extension to the TAM, using the medical Laboratory Information Systems (LIS)--Electronic Health Records (EHR) interface as the medium. The TAM posits that it is the individual's attitude that determines whether a system will be used or rejected which is further influenced by the individual's perceived ease of use (PEOU) and perceived usefulness (PU). Davis particularly argued that a user who finds a system easy to use must also think it is useful. Medical doctors from two medical organizations were asked to participate in a psychometric online survey based on their prior attitudes and beliefs in adopting new technologies in their practice. The results suggested that perceived usefulness has a significance influence on the behavioral intent to use. Surprisingly, perceived ease of use was not proven to be an effective predictor of the behavioral intent to use the medical LIS-EHR interface technology. Attributes of change was the only variable from the Organizational Readiness Change Theory that was found to be a viable external variable for the Technology Acceptance Model. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]