ERIC Number: EJ1036388
Record Type: Journal
Publication Date: 2014-Aug
Abstractor: As Provided
Hands-on Electrospray Ionization-Mass Spectrometry for Upper-Level Undergraduate and Graduate Students
Stock, Naomi L.; March, Raymond E.
Journal of Chemical Education, v91 n8 p1244-1247 Aug 2014
Electrospray ionization-mass spectrometry (ESI-MS) is a powerful technique for the detection, identification, and quantification of organic compounds. As mass spectrometers have become more user-friendly and affordable, many students--often with little experience in mass spectrometry--find themselves needing to incorporate mass spectrometry into their research. Herein, a hands-on laboratory experiment for upper-level undergraduate and graduate students to investigate ESI-MS is described. This experiment provides students with the opportunity to observe and use instrumentation discussed in class, to investigate various modes of operation, to compare triple-stage quadrupole (TSQ) with quadrupole linear ion trap (QLIT) instrumentation, and to decide upon the optimum approach for incorporation of mass spectrometry into their research.
Descriptors: College Science, Science Instruction, Graduate Study, Undergraduate Study, Spectroscopy, Molecular Structure, Chemistry, Science Laboratories, Laboratory Experiments, Scientific Concepts, Science Process Skills
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: firstname.lastname@example.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Authoring Institution: N/A