Information graphics, or "infographics," are widely used to convey complex science and its importance to society. To be educated consumers and citizens, students need to understand and be critical of information presented in graphical form. Researchers, accordingly, have called for fostering the "representational competence" of young people (diSessa and Sherin 2000) and developing their "multimodal literacy" (Jewitt and Kress 2003). Graphical representations of data are also emphasized in standards and high-stakes assessments. Interpreting and creating graphical representations are part of the "Next Generation Science Standards" (NGSS Lead States 2013), and students are assessed on these skills in the Program for International Student Assessment (PISA), the ACT, and state accountability exams. This article describes models for integrating infographics into high school science classes. The goal is to teach students graphical representation, while building their 21st-century data and information literacy.