ERIC Number: EJ1120583
Record Type: Journal
Publication Date: 2016-Dec
Abstractor: As Provided
Stable, Long-Term, Spatial Memory in Young and Aged Rats Achieved with a One Day Morris Water Maze Training Protocol
Barrientos, Ruth M.; Kitt, Meagan M.; D'Angelo, Heather M.; Watkins, Linda R.; Rudy, Jerry W.; Maier, Steven F.
Learning & Memory, v23 n12 p699-702 Dec 2016
Here, we present data demonstrating that a 1 d Morris water maze training protocol is effective at producing stable, long-term spatial memory in both young (3 mo old) and aged (24 mo old) F344xBN rats. Four trials in each of four sessions separated by a 2.5 h ISI produced robust selective search for the platform 1 and 4 d after training, in both age groups. A 1 h ISI protocol did not produce good retention. Also, compressing the trials into just two sessions separated by a 2.5 h ISI produced limited retention in only young rats.
Descriptors: Animals, Animal Behavior, Spatial Ability, Training, Long Term Memory, Age Differences, Recall (Psychology)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A