Anorexia nervosa has received considerable attention lately because of its increased incidence, potential danger, and resistance to treatment. A review of the literature on anorexia nervosa suggests that, although it is characterized by complex interrelated psychological and physiological processes, it is often conceptualized and treated in unifocal or unimodal terms. Even when more eclectic, multi-dimensional orientations are employed, they fail to provide a conceptual framework or a systematic approach. Perhaps for these reasons, treatment effects have been circumscribed and relapse rates high. The multimodal therapy model of Arnold Lazarus obviates many of the deficits cited, in offering a comprehensive, systematic, holistic approach to assessment and treatment. This multimodal approach focuses on the areas of behavior, affect, sensory, imagery, cognitive, interpersonal, and drugs. Therapy methods include identifying the triggering modalities, "bridging" the client from one modality to another, and tracking the intervening modalities. A multimodal case study employing the Lazarus method for an adolescent anorexic girl is discussed. (ABL)