Considerable evidence has demonstrated a critical role for the nucleus accumbens (NAc) in the acquisition and flexibility of behavioral strategies. These processes are guided by the activity of two discrete neuron types, dopamine D1- or D2-receptor expressing medium spiny neurons (D1-/D2-MSNs). Here we used the IntelliCage, an automated…

The increasingly severe school violence has become an influential and notorious worldwide problem. The attribution of school violence determines the formulation of coping strategies. Unlike the analysis of family, psychological and social factors, long-term front-line work and follow-up studies have found that student violence's physiological…

Children with ADHD are often described as experiencing deficits in executive function. Two key areas of concern are inhibition, the ability to refrain from a dominant response when needed, and updating, the ability to revise or update incoming information. The purpose of this manuscript is to combine disparate lines of research to help establish a…

Background: International literature has underlined the complex interplay between genetic and environmental variables in shaping children's emotional-behavioral functioning. Objective: This study aimed to explore the dynamic relationship between children's Dopamine Transporter (DAT1) genotype and methylation, and maternal and paternal affective…

This study investigated the interactive effect of Dopamine D2 receptor gene Taq 1A ("DRD2" rs1800497) and parental behavior on creativity and examined whether a potential gene--parenting interaction (G × E) would be consistent with one of two models of gene--environment interplay (diathesis-stress vs. differential susceptibility). In a…

The purpose of this paper is to explain and establish a link between social-psychological and biological explanations of self-efficacy theory. Specifically, the paper uses a hypothetical rock climbing program to illustrate how a practitioner could enhance the four sources of self-efficacious beliefs (enactive attainment, vicarious experience,…

The US Department of Justice released the final report on school violence and showed that middle school is the age when violence is high, accounting for more than 70% of all violence cases (Zweig et al., 2013). After having perpetrated, the probability that the perpetrator will commit violence again will increase significantly (Office of the…

Cognitive deficits and particularly deficits in working memory (WM) capacity are common features in neuropsychiatric disorders. Understanding the underlying mechanisms through which WM capacity can be improved is therefore of great importance. Several lines of research indicate that dopamine plays an important role not only in WM function but also…

A lab appropriate to introduce voltammetric techniques and basic electrochemical parameters is described in this work. It is suitable to study theoretical concepts of electrochemistry in an applied way for analytical undergraduate courses. Two electroactive species, hexaammineruthenium and dopamine, are used as simple redox systems. Screen-printed…

Previous findings indicate that the acquisition and consolidation of recognition memory involves dopaminergic activity. Although dopamine deregulation has been observed in Alzheimer's disease (AD) patients, the dysfunction of this neurotransmitter has not been investigated in animal models of AD. The aim of this study was to assess, by in vivo…

Most existing models of dopamine and learning in Parkinson disease (PD) focus on simulating the role of basal ganglia dopamine in reinforcement learning. Much data argue, however, for a critical role for prefrontal cortex (PFC) dopamine in stimulus selection in attentional learning. Here, we present a new computational model that simulates…

We used a technique known as reach tracking to investigate how individual differences in working memory capacity (WMC) relate to the functioning of two processes proposed to underlie cognitive control: a threshold adjustment process that temporarily inhibits motor output in response to signals of conflict and a controlled selection process that…

Several attempts have been made previously to provide a biological grounding for cognitive architectures by relating their components to the computations of specific brain circuits. Often, the architecture's action selection system is identified with the basal ganglia. However, this identification overlooks one of the most important features of…

The sensory properties of a reward-paired cue (a conditioned stimulus; CS) may impact the motivational value attributed to the cue, and in turn influence the form of the conditioned response (CR) that develops. A cue with multiple sensory qualities, such as a moving lever-CS, may activate numerous neural pathways that process auditory and visual…

Behavioral activation that is associated with incentive-reward motivation increases in adolescence relative to childhood and adulthood. This quadratic developmental pattern is generally supported by behavioral and experimental neuroscience findings. It is suggested that a focus on changes in dopamine neurotransmission is informative in…