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Leong, Jhaque; Ackroyd, Nathan C.; Ho, Karen – Journal of Chemical Education, 2014
The synthesis of N-methoxycarbonyl-2-imidazolidone, an analogue of biotin, was conducted by organic chemistry students and confirmed using FT-IR and H NMR. Spectroscopy students used FT-IR to measure the rate of hydrolysis of the product and determined the rate constant for the reaction using the integrated rate law. From the magnitude of the rate…
Descriptors: Science Instruction, Science Laboratories, Spectroscopy, Kinetics