NotesFAQContact Us
Search Tips
Back to results
Peer reviewed Peer reviewed
Direct linkDirect link
ERIC Number: EJ907489
Record Type: Journal
Publication Date: 2010
Pages: 6
Abstractor: As Provided
ISSN: ISSN-1470-8175
My Dog's Cheeks: A PBL Project on Collagen for Cell Biology and Genetics Courses
Casla, Alberto Vicario; Zubiaga, Isabel Smith
Biochemistry and Molecular Biology Education, v38 n6 p410-415 Nov-Dec 2010
Students often have an oversimplified view of biological facts, which may hinder subsequent understanding when conceptual complexity gives rise to cognitive conflicts. To avoid this situation here, we present a PBL approach for the analysis of Ehlers-Danlos syndrome (EDS), which integrates a variety of topics in cell biology, genetics, and molecular biology, and it is used to illustrate the inherent complexities in some classical biological concepts. Students of two different courses analyze phenotypic, cellular, and molecular characteristics of EDS. Effect of mutations on collagen synthesis on collagen genes' expression and regulation or on connective tissues is reviewed and discussed. Information retrieval is used to develop students' skills in web-based molecular biology tools. Student interest and motivation is increased with the development of diagnostic protocols for a tissue biopsy and for an EDS causing mutation. Expected learning outcomes after completion of the project are also presented. (Contains 5 figures and 1 table.)
John Wiley & Sons, Inc. Subscription Department, 111 River Street, Hoboken, NJ 07030-5774. Tel: 800-825-7550; Tel: 201-748-6645; Fax: 201-748-6021; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: Students; Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A