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Direct linkBraverman, Nancy E.; D'Agostino, Maria Daniela; MacLean, Gillian E. – Developmental Disabilities Research Reviews, 2013
The peroxisome biogenesis disorders (PBD) are a heterogeneous group of autosomal recessive disorders in which peroxisome assembly is impaired, leading to multiple peroxisome enzyme deficiencies, complex developmental sequelae and progressive disabilities. Mammalian peroxisome assembly involves the protein products of 16 "PEX" genes;…
Descriptors: Genetic Disorders, Congenital Impairments, Biochemistry, Symptoms (Individual Disorders)
Tang, Bor Luen; Teng, Felicia Yu Hsuan – Biochemistry and Molecular Biology Education, 2005
The process of protein biogenesis culminates in its correct targeting to specific subcellular locations where it serves a function. Contemporary molecular and cell biology investigations often involve the exogenous expression of epitope- or fluorescent protein-tagged recombinant molecules as well as subsequent analysis of protein-protein…
Descriptors: Topology, Scientific Concepts, Biochemistry, Cytology
