The concerns of this article are the unacceptable status of Science, Technology and Mathematics (STM) Education in the Caribbean and how to improve the students' achievement in the subjects involved through the instrumentality of better preparation of teachers by the Colleges and University faculties training teachers in the region. The index for measuring development among nations of the world is the level of scientific and technological advancement because the factors that influence development are based on human ability to explore, invest and utilize the natural endowments available in the nation. In other words, no nation can attain any reasonable level of development without meeting the vital demands of development particularly in the areas of science, technology and mathematics. Therefore, the article begins with the presentation of the importance and the status of STM education using the mirror of science students' achievement at global level. Moreover, it is established that the Caribbean education also has some challenges to deal with in the areas of science, technology and mathematics education. The tertiary institutions, particularly the colleges training teachers and the universities are then challenged with suggestions of what they can or should do in teacher preparation that may have direct impact on improving the science students' achievement in the Caribbean.