Project-based learning (PBL) and Blended Learning (BL) have been widely used in universities. There are some empirical teaching researches on PBL in the BL environment for some specific courses, but for the combination of PBL and BL, there is as yet no universal teaching model. This article puts forward a new universal teaching mode: Project-Based Blended Learning (PBBL) and describes a teaching experiment in applying PBBL. Firstly, the design idea of PBBL is discussed. Secondly, taking a course on Single Chip Microcomputers (SCM) as an example, the strategies of selecting, designing and controlling the core teaching elements are given, and the complete implementation plan and concrete methods are described. The teaching case shows that the PBBL gives full play to the advantages of BL and PBL, and can effectively improve students' abilities of self-learning, practical application and innovation.