The study aimed at investigating the effect of instruction through telegram groups on the learners' reading comprehension. Moreover, it investigated that whether there is any difference between two genders of the experimental groups in reading comprehension ability. For this purpose, 147 subjects were selected. To homogenize them, a standard placement test was used and the test results reduced the number of participants to 103 learners among which 55 ones were chosen randomly as the experimental group consisting of 29 females and 26 males. The rest were assigned as the control group including 26 females and 22 males. At the first session, a researcher-made reading comprehension test was applied as the pretest. Twelve passages were taught through telegram groups for experimental groups and the same passages were taught in the classroom through the traditional way of reading comprehension instruction. In the last session, the same researcher-made reading comprehension test was administered as the post-test. The results portrayed that instruction through telegram groups has a significant effect on the Intermediate students' reading comprehension ability. Furthermore, it was determined that there was no significant difference between two male and female experimental groups in the terms of reading comprehension ability.