Two studies examined the psychometric properties of the Adult Manifest Anxiety Scale-College Version (AMAS-C) scores among U.S. college students. In Study 1,300 college students were administered the AMAS-C. Confirmatory factor analyses (CFAs) indicated that the five-factor model (four anxiety factors and one lie factor) with a higher order factor provided the best fit to the data. In Study 2,177 college students were administered the AMAS-C and external measures and correlational analyses indicated support for the convergent and discriminant validity of the AMAS-C scores. Implications of the findings of the studies for mental health professionals who work with college students are discussed.