The interdisciplinary National Science Foundation-funded research project "Teaching Critical Thinking Skills in Science with 'sInvestigator'" supports undergraduate students as they explore scientific topics and problems with the use of an intelligent computer system called "sInvestigator" (science Investigator). The research team will share results from the first year of this three-year project. "sInvestigator" creates a real-time graphical model of evidentiary reasoning based on student data entry and justifications. Preliminary findings indicate that integrating lecture-based instruction with collaborative use of "sInvestigator" to engage students in evidence-based reasoning builds information literacy within the content area. The research team also concluded that "sInvestigator" design principles have the potential to build argumentation skills in other disciplines.