During the last few years, ongoing developments in the technological field of Cloud computing have initiated discourse on the potential of the Cloud to be systematically exploited in educational contexts. Research interest has been stimulated by a range of advantages of Cloud technologies (e.g. adaptability, flexibility, scalability, accessibility, cost effectiveness). For these reasons, there have already been efforts concerned with the educational uptake of the Cloud at different scale levels (mainly at the institutional and regional level). Apart from that, there are also larger-scale initiatives taking the form of research projects (e.g. the Rural School Cloud project). Nevertheless, most practices have been mainly shaped by the application of economic policies rather than systematic research. In this emerging situation, the aim of this paper is to present the activities of a European network, which has been set up to research how education should adapt and respond to advancements in Cloud computing. The innovative character of the network is that it attempts a holistic approach to the investigation of the effects of Cloud technologies on formal education by targeting at all involved stakeholders, and contexts of use, at all educational levels. By analytically presenting the adopted methodology and network members' vision for Cloud-based, student-centered learning and teaching, our aim is to provide a detailed account of the network's research activities. [For the full proceedings, see ED562093.]