Most institutions are collecting evidence of student learning, but it is not clear how these results are being used to improve student outcomes. To learn more about what colleges and universities are doing to use assessment data productively to inform and strengthen undergraduate education, the National Institute for Learning Outcomes Assessment conducted nine case studies. This report synthesizes the insights from these individual studies to discern promising practices in using information about student learning. Institutional behavior appears to be generally consistent with the Principles of Effective Assessment Practice identified by Banta and Associates (2002). For example, the case study institutions took advantage of calls for accountability to leverage internal improvement efforts, communicated widely about assessment efforts and results, and took time to reflect on their assessment activities and results. Equally important, the case study institutions aligned their assessment work with organizational structures and cultures, and focused their assessment efforts on specific problems or questions. The report concludes with lessons learned and reflective questions to help institutions advance their own assessment efforts within their specific institutional contexts. Appended are: (1) Methodology; and (2) Annotated Case Study List. [Funding for this paper was provided by the College of Education at the University of Illinois.]