One of the four guiding principles of the National Science Education Standards is simply "science for all students" (NRC 1996). This principle underscores the belief that all students, regardless of race, gender, or disability, should have the opportunity to learn and understand the essential science content described in the Standards. Because of increasingly widespread inclusion practices and more thorough identification procedures, students with documented learning disabilities (LD) are becoming a larger percentage of the science classroom. Between 5% and 10% of all K-12 children are identified as having a specific learning disability (Department of Education 2002; Kavale and Forness 1995) and it is anticipated that this number will grow. LD students often struggle with academic challenges in both their general high school curriculum and in their science classes. Between 36% and 56% of LD students leave high school without a diploma or certificate of completion (Collett-Klingenberg 1998), and LD students score almost one standard deviation lower on science achievement tests than those students without disabilities (Anderman 1998). Using a biology unit on cell transport as the content anchor, the authors present six principles and practical examples, which were developed as a follow-up to the "Biology Success" project (an NSF grant-funded project designed to give introductory high school and college biology instructors ideas, tools, and inspiration for teaching diverse learners). By applying the principles and practices described in this article (drawn from a review of science teaching and special education literature and the authors' combined 20-year plus years of experience working at a school designed to meet the needs of students with LD and/or attention deficit disorders), science teachers can better serve the personal and academic needs of LD students and thus help realize the vision of the National Science Education Standards guiding principle of "science for all."