This issue brief describes the programs and systems of the MDRC Center for Data Insights. Ranging from simple descriptive summaries to advanced machine learning algorithms, the Center's eight current projects aim to use institutions' increasingly rich data to provide new insights that can help refine and target their client's services: (1) Temporary Assistance for Needy Families Data Innovations (TDI); (2) Partnership with the Center for Employment Opportunities (CEO) for Predictive Analytics; (3) Subprime Lending Data Exploration Project; (4) The Pretrial Justice Reform Study; (5) New Visions for Public Schools (NVPS) Researcher Partnership for Predictive Analytics; (6) Using Machine Learning to Predict Third-Grade Reading Proficiency; (7) The Long-Term Outcomes Project; and (8) Chicago Community Networks Study.