Interagency communication and collaboration is a key principle and practice in addressing the unmet educational needs of youth in the juvenile justice and child welfare systems. When child-serving agencies communicate and work with each other, and are committed to coordinating services and supports for the youth and families they serve, they become part of a more integrated system. Such a system may prove more efficient and effective than one in which child welfare, juvenile justice, education, and related agencies work in silos. This guide is designed to provide agency administrators and staff with concrete strategies and real-life examples for implementing three practices geared to increasing effective interagency communication and collaboration. The National Evaluation and Technical Assistance Center for the Education of Children and Youth Who Are Neglected, Delinquent, or At-Risk (NDTAC) hopes this guide promotes administrators of Title I, Part D, and other Federal education-related funds to consider how the programs funded by these dollars can promote greater communication and collaboration between child-serving agencies and, in turn, improve academic and related outcomes for the youth they serve. A list of resources and examples is provided.