This article aims to study both similarities and differences in female students' creativity between Mainland China and Taiwan. As two main aspects influencing creativity, playfulness and humor are especially focused on in this comparative study. Empirical data were collected from 831 students in Mainland China and 703 students in Taiwan. Based on data analysis, we find common characteristics, gender differences, and regional differences in the creativity of female postgraduate students. The female students in both regions are less confident in their abilities in scientific research and innovative behavior than males. The female students in Mainland China are less confident in playfulness, humor, and creative life experience than their counterparts. The female students in Taiwan are more masculine than their counterparts in Mainland China.