A hands-on approach to science is highly desirable because an inquiry approach to science greatly promotes learning. However when students and teachers manipulate glassware, chemical, and other materials, accidents will happen. Because of this, risk management and safety procedures become an important, integral part of the science curriculum. This booklet presents the guidelines to having an effective safety program. Included are the following sections: (1) general safety instruction; (2) fire protection; (3) eye protection; (4) laboratory chemical inventory, disposal, storage, and labeling; (5) facilities; and (6) references. A student safety contract, safety rules for chemistry, biology, and physical science students, an explosives list, general housekeeping rules, and a list of resource personnel are appended. (KR)