The Pyramid Model for Supporting Social Emotional Competence in Infants and Young Children (Hemmeter, Fox, & Snyder, 2013), or the Pyramid Model, is a conceptual framework focused on systemic and sustained implementation of evidence-based practices (EBP) related to promoting social emotional competence and preventing challenging behaviors in young children. The Pyramid Model is a research-based, multi-tiered support system to support early childhood (EC) professionals in promotion, prevention, and intervention practices (Hemmeter, Snyder, Fox, & Algina, 2016). The federal policy statement on eliminating preschool suspension and expulsion described the Pyramid Model as an effective approach to promoting social emotional competence and addressing challenging behavior (U.S. Departments Health and Human Services and U.S. Department of Education, 2015). There is growing evidence that this model is an effective approach to professional development likely to yield positive child outcomes (Hemmeter et al., 2016) and reduce rates of expulsion for challenging behavior (Vinh et al., 2016). This article documents the inception, development, and evaluation of Pyramid Plus: The Colorado Center for Social Emotional Competence and Inclusion, or the Pyramid Plus Center, as an example of statewide implementation of the Pyramid Model. The goal of the Pyramid Plus Center is to build the capacity of EC programs across Colorado to use EBP for improving children's social and emotional competence, advancing high-quality inclusion, and reducing overall suspensions and expulsions of preschool children. The initiatives used to reach this goal are: (1) providing training and technical assistance (T/TA); (2) certifying trainers and coaches across the state; (3) partnering with communities and programs; and (4) building state infrastructure. Recommendations for scaling up and sustaining Pyramid Model practices also are provided.