The present study examined the role of school connectedness in mediating the relations of social skills and school climate of diversity (SCD) to life satisfaction (LS) among school-aged children. This study also investigated whether there is any gender difference in relationships. Participants included 873 elementary school students in Grades 4 through 6. The results of the structural equation modeling supported the partial mediating role of school connectedness, indicating that social skills and SCD lead to LS both directly and indirectly through enhanced school connectedness. Multigroup analysis demonstrated that the direct path from the SCD to LS was significant only for boys, while other paths are invariant across gender. Implications are addressed for school-based interventions to promote school connectedness and LS.