While the Common Core State Standards and state learning standards guide teachers in what mathematical content knowledge should be addressed as well as the processes and proficiencies necessary for developing mathematical competence, several student- and teacher-related factors may hinder student access to the general education curriculum for secondary students with emotional and behavioral disorders. Consequently, secondary students with emotional and behavioral disorders often fail to receive equitable, high-quality mathematics instruction that is age-appropriate. The authors identified the challenges associated with teaching mathematics to secondary students with emotional and behavioral disorders and provided practical suggestions, on the basis of the limited existing research base, to help special educators understand how to teach mathematics to secondary students with emotional and behavioral disorders.