A survey of over 11 000 undergraduate students' knowledge and attitudes related to science and technology over a 22-year period included statements that probed faith-based beliefs and various aspects of pseudoscience belief and superstition. The results reveal that nonscientific ways of thinking are resistant to formal instruction, changing surprisingly little over the course of a college career that typically includes three science courses. The level of basic science knowledge among undergraduates is only weakly coupled to attitudes towards pseudoscience, and it coexists with attitudes and beliefs that are faith-based. These results provide a challenge for educators who seek to improve the generally low level of science literacy among college graduates and members of the general public. (Contains 4 figures and 3 tables.)