This article critically reviews empirical correlates of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2; Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989), based on several validation studies conducted with different racial, ethnic, and cultural groups. A major critique of the reviewed MMPI-2 studies was focused on the use of extratest measures with origins in a purely Western worldview. To address significant ethical issues, future studies that investigate the validity of using the MMPI-2 with persons from diverse cultural backgrounds must incorporate extratest measures grounded in relevant cultural systems. Using culturally and contextually informed extratest measures to identify empirical correlates and validate the MMPI-2 will improve the research in this area by leaps and bounds.