Four experiments investigate the influence of topic status and givenness on how speakers and writers structure sentences. The results of these experiments show that when a referent is previously given, it is more likely to be produced early in both sentences and word lists, confirming prior work showing that givenness increases the accessibility of given referents. When a referent is previously given and assigned topic status, it is even more likely to be produced early in a sentence, but not in a word list. Thus, there appears to be an early mention advantage for topics that is present in both written and spoken modalities but is specific to sentence production. These results suggest that information-structure constructs, like topic, exert an influence that is not based only on increased accessibility but also reflects mapping to syntactic structure during sentence production. (Contains 2 figures, 5 tables, and 3 footnotes.)