ERIC Number: EJ951203
Record Type: Journal
Publication Date: 2012-Jan
Abstractor: As Provided
Reference Count: 34
Enhanced Cortisol Response to Stress in Children in Autism
Spratt, Eve G.; Nicholas, Joyce S.; Brady, Kathleen T.; Carpenter, Laura A.; Hatcher, Charles R.; Meekins, Kirk A.; Furlanetto, Richard W.; Charles, Jane M.
Journal of Autism and Developmental Disorders, v42 n1 p75-81 Jan 2012
Children with Autism often show difficulties in adapting to change. Previous studies of cortisol, a neurobiologic stress hormone reflecting hypothalamic-pituitary-adrenal (HPA) axis activity, in children with autism have demonstrated variable results. This study measured cortisol levels in children with and without Autism: (1) at rest; (2) in a novel environment; and (3) in response to a blood draw stressor. A significantly higher serum cortisol response was found in the group of children with autism. Analysis showed significantly higher peak cortisol levels and prolonged duration and recovery of cortisol elevation following the blood-stick stressor in children with autism. This study suggests increased reactivity of the HPA axis to stress and novel stimuli in children with autism.
Descriptors: Stimuli, Autism, Stress Variables, Biochemistry, Adjustment (to Environment), Neurology, Biology, Children, Physiology, Change, Diagnostic Tests
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A