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ERIC Number: EJ950492
Record Type: Journal
Publication Date: 2006
Pages: 36
Abstractor: As Provided
Reference Count: 0
ISSN: ISSN-0021-9630
Gene-Environment Interplay and Psychopathology: Multiple Varieties but Real Effects
Rutter, Michael; Moffitt, Terrie E.; Caspi, Avshalom
Journal of Child Psychology and Psychiatry, v47 n3-4 p226-261 Mar-Apr 2006
Gene-environment interplay is a general term that covers several divergent concepts with different meanings and different implications. In this review, we evaluate research evidence on four varieties of gene-environment interplay. First, we consider epigenetic mechanisms by which environmental influences alter the effects of genes. Second, we focus on variations in heritability according to environmental circumstances. Third, we discuss what is known about gene-environment correlations. Finally, we assess concepts and findings on the interaction between specific identified genes and specific measured environmental risks. In order to provide an understanding of what may be involved in gene-environment interplay, we begin our presentation with a brief historical review of prevailing views about the role of genetic and environmental factors in the causation of mental disorders, and we provide a simplified account of some of the key features of how genes "work".
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A