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ERIC Number: EJ943581
Record Type: Journal
Publication Date: 2011-Sep
Pages: 18
Abstractor: As Provided
Reference Count: 29
ISSN: ISSN-1362-3613
Longitudinal Changes in Scores on the Autism Diagnostic Interview-Revised (ADI-R) in Pre-School Children with Autism: Implications for Diagnostic Classification and Symptom Stability
Soke, Gnakub Norbert; Philofsky, Amy; Diguiseppi, Carolyn; Lezotte, Dennis; Rogers, Sally; Hepburn, Susan
Autism: The International Journal of Research and Practice, v15 n5 p545-562 Sep 2011
We prospectively examined mean changes in Autism Diagnostic Interview-Revised (ADI-R) Total and Domains scores and stability of the ADI-R diagnostic classification in 28 children with autism initially assessed at age 2-4 years and reassessed 2 years later. Mean Total, Social Interaction, and Communication scores decreased significantly from Time 1 to Time 2 Restricted/repetitive Domain mean scores did not change over time. The ADI-R diagnostic classification was stable in 67% of children using the current published criteria. The stability increased to 78% when a modified criterion was used in the Restricted/repetitive Domain and to 88% when the broader ASD criteria were used. Among pre-schoolers with autism, parent-reported symptoms decreased significantly at two-year follow-up in Social and Communication Domains but not in the Restricted/repetitive Domain. However, ADI-R diagnostic classification remained relatively stable over time. Revising ADI-R diagnostic criteria in the Restricted/repetitive Domain or including the broader ASD criteria may improve its sensitivity and diagnostic stability in younger children. (Contains 2 tables and 1 figure.)
SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Assessments and Surveys: Mullen Scales of Early Learning; Autism Diagnostic Observation Schedule