ERIC Number: EJ941750
Record Type: Journal
Publication Date: 2011-Mar
Abstractor: As Provided
Reference Count: 0
Elevated Amygdala Response to Faces following Early Deprivation
Tottenham, N.; Hare, T. A.; Millner, A.; Gilhooly, T.; Zevin, J. D.; Casey, B. J.
Developmental Science, v14 n2 p190-204 Mar 2011
A functional neuroimaging study examined the long-term neural correlates of early adverse rearing conditions in humans as they relate to socio-emotional development. Previously institutionalized (PI) children and a same-aged comparison group were scanned using functional magnetic resonance imaging (fMRI) while performing an Emotional Face Go/Nogo task. PI children showed heightened activity of the amygdala, a region that supports emotional learning and reactivity to emotional stimuli, and corresponding decreases in cortical regions that support perceptual and cognitive functions. Amygdala activity was associated with decreased eye-contact as measured by eye-tracking methods and during a live dyadic interaction. The association between early rearing environment and subsequent eye-contact was mediated by amygdala activity. These data support the hypothesis that early adversity alters human brain development in a way that can persist into childhood, and they offer insight into the socio-emotional disturbances in human behavior following early adversity.
Descriptors: Emotional Disturbances, Brain, Emotional Development, Neurological Organization, Child Rearing, Social Development, Institutionalized Persons, Comparative Analysis, Diagnostic Tests, Brain Hemisphere Functions, Stimuli, Eye Movements, Correlation, Child Development, Developmental Psychology
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A